Deciphering peculiar protein-protein interacting modules in Deinococcus radiodurans
Identifieur interne : 000079 ( Main/Exploration ); précédent : 000078; suivant : 000080Deciphering peculiar protein-protein interacting modules in Deinococcus radiodurans
Auteurs : Karim Mezhoud [Tunisie] ; Haïtham Sghaier [Tunisie] ; Insaf Barkallah [Tunisie]Source :
- Biology Direct [ 1745-6150 ] ; 2009.
Descripteurs français
- KwdFr :
- MESH :
- composition chimique : Protéines bactériennes.
- métabolisme : Deinococcus, Protéines bactériennes.
- Bases de données de protéines, Liaison aux protéines, Simulation numérique.
English descriptors
- KwdEn :
- MESH :
- chemical , chemistry : Bacterial Proteins.
- chemical , metabolism : Bacterial Proteins.
- metabolism : Deinococcus.
- Computer Simulation, Databases, Protein, Protein Binding.
Abstract
Interactomes of proteins under positive selection from ionizing-radiation-resistant bacteria (IRRB) might be a part of the answer to the question as to how IRRB, particularly
Url:
DOI: 10.1186/1745-6150-4-12
PubMed: 19356244
PubMed Central: 2672081
Affiliations:
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Le document en format XML
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for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Unit of Microbiology and Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana</wicri:regionArea></affiliation></author><author><name sortKey="Barkallah, Insaf" sort="Barkallah, Insaf" uniqKey="Barkallah I" first="Insaf" last="Barkallah">Insaf Barkallah</name><affiliation wicri:level="1"><nlm:aff id="I1">Unit of Microbiology and Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Unit of Microbiology and Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno 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Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana</wicri:regionArea></affiliation></author><author><name sortKey="Sghaier, Haitham" sort="Sghaier, Haitham" uniqKey="Sghaier H" first="Haïtham" last="Sghaier">Haïtham Sghaier</name><affiliation wicri:level="1"><nlm:aff id="I1">Unit of Microbiology and Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Unit of Microbiology and Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana</wicri:regionArea></affiliation></author><author><name sortKey="Barkallah, Insaf" sort="Barkallah, Insaf" uniqKey="Barkallah I" first="Insaf" last="Barkallah">Insaf Barkallah</name><affiliation wicri:level="1"><nlm:aff id="I1">Unit of Microbiology and Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana, Tunisia</nlm:aff><country xml:lang="fr">Tunisie</country><wicri:regionArea>Unit of Microbiology and Molecular Biology, National Center for Nuclear Sciences and Technologies (CNSTN), Sidi Thabet Technopark, 2020, Ariana</wicri:regionArea></affiliation></author></analytic><series><title level="j">Biology Direct</title><idno type="eISSN">1745-6150</idno><imprint><date when="2009">2009</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Bacterial Proteins (chemistry)</term><term>Bacterial Proteins (metabolism)</term><term>Computer Simulation (MeSH)</term><term>Databases, Protein (MeSH)</term><term>Deinococcus (metabolism)</term><term>Protein Binding (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Bases de données de protéines (MeSH)</term><term>Deinococcus (métabolisme)</term><term>Liaison aux protéines (MeSH)</term><term>Protéines bactériennes (composition chimique)</term><term>Protéines bactériennes (métabolisme)</term><term>Simulation numérique (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="chemistry" xml:lang="en"><term>Bacterial Proteins</term></keywords><keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Bacterial Proteins</term></keywords><keywords scheme="MESH" qualifier="composition chimique" xml:lang="fr"><term>Protéines bactériennes</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Deinococcus</term></keywords><keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Deinococcus</term><term>Protéines bactériennes</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Computer Simulation</term><term>Databases, Protein</term><term>Protein Binding</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Bases de données de protéines</term><term>Liaison aux protéines</term><term>Simulation numérique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Interactomes of proteins under positive selection from ionizing-radiation-resistant bacteria (IRRB) might be a part of the answer to the question as to how IRRB, particularly <italic>Deinococcus radiodurans </italic>R<sub>1 </sub>(Deira), resist ionizing radiation. Here, using the Database of Interacting Proteins (DIP) and the Protein Structural Interactome (PSI)-base server for PSI map, we have predicted novel interactions of orthologs of the 58 proteins under positive selection in Deira and other IRRB, but which are absent in IRSB. Among these, 18 domains and their interactomes have been identified in DNA checkpoint and repair; kinases pathways; energy and nucleotide metabolisms were the important biological processes that were found to be involved. This finding provides new clues to the cellular pathways that can to be important for ionizing-radiation resistance in Deira.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Tunisie</li></country></list><tree><country name="Tunisie"><noRegion><name sortKey="Mezhoud, Karim" sort="Mezhoud, Karim" uniqKey="Mezhoud K" first="Karim" last="Mezhoud">Karim Mezhoud</name></noRegion><name sortKey="Barkallah, Insaf" sort="Barkallah, Insaf" uniqKey="Barkallah I" first="Insaf" last="Barkallah">Insaf Barkallah</name><name sortKey="Sghaier, Haitham" sort="Sghaier, Haitham" uniqKey="Sghaier H" first="Haïtham" last="Sghaier">Haïtham Sghaier</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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